One of the most effective over-the-counter arrhythmia-correcting drugs is Asparkam. The essence of its action is the normalization of metabolism and electrolytes. It is a metabolite, a source of potassium and magnesium. Due to this, it normalizes the heart rhythm. The medicine belongs to the means of the most democratic price segment, but this does not prevent it from being more effective than many expensive analogues. Asparks are loved by athletes for the opportunity to lose extra pounds against the backdrop of an increased drinking regime.
Composition
Asparkam is available in the form of tablets and solution for injection. The package contains 50 pieces of pills or 10 ampoules of 5, 10 ml.
- Each tablet contains 0.2 g of potassium and magnesium, as well as excipients for the cachet.
- Asparkam's solution contains anhydrous magnesium aspartate - 40 mg and potassium - 45 mg. This is equivalent to 3 mg of pure magnesium and 10 mg of pure potassium. In addition, the injectable form contains sorbitol and water.
Potassium provides the passage of nerve impulses, exhibits diuretic properties and plays a major role in muscle contraction. Magnesium is responsible for enzymatic activity, participates in the transport of ions and cell growth.
The mechanism of action is to correct metabolic processes with potassium and magnesium. These elements easily overcome the cell membrane and make up for the deficiency of microelements lost under the influence of time or pathological changes. The normalizing electrolyte balance leads to a decrease in the conductivity of the myocardium, extinguishes its excitability and enables the electrical impulses of the cardiac conduction system to work in the usual mode.
At the same time, metabolic processes improve, the myocardium's susceptibility to cardiac glycosides becomes better, since their toxicity drops sharply. Coronary vessels also respond to changes that occur, since the normal rhythmic contractility of the heart allows them to provide an optimal blood supply to organs and tissues with nutrients and oxygen.
Magnesium ions activate ATP, which balances the flow of sodium into the intercellular space and potassium into the intracellular space. A decrease in the concentration of Na + inside the cell blocks the exchange of calcium and sodium in vascular smooth muscles, which automatically relaxes them. The growth of K + stimulates the production of ATP - a source of energy, glycogen, proteins and acetylcholine, which prevents cardiac ischemia and cellular hypoxia.
Asparkam enters the bloodstream through the digestive tract, and from there - in the form of aspartate into the myocardium, where it begins to work to improve metabolism.
Properties
They are due to the combined effect of potassium and magnesium on the heart muscle and help to restore it after a heart attack. K + improves cardiac contractility by reducing excitability and improving muscle conductivity. It expands the lumen of the great vessels of the heart. Magnesium stimulates the synthesis of amino acids necessary for replenishing a muscle tissue defect and stimulates cell division, contributing to speedy regeneration.
These properties are used in the treatment of glaucoma and high intracranial pressure. The normalization of metabolism and electrolyte balance relieve almost all negative symptoms associated with vascular overload. A side effect is faster muscle growth, which has proven to be important for athletes. Therefore, Asparkam is quite popular in power sports.
Potassium and magnesium
Cardiologists are constantly talking about the importance of these trace elements. There is nothing surprising in this. The rhythm of heart contractions is determined by the high-quality work of the myocardial conduction system, in which impulses are generated independently, and, passing through bundles of special nerve fibers, they activate the frequency of contraction of the atria and ventricles in a certain sequence. The normal conductance of these fibers depends on the concentration of magnesium and potassium in them.
The heartbeat is normal, which means that the person also feels good, since each organ receives appropriate nutrition and oxygen on time and with a clear sequence. With a lack of magnesium, problems begin in the coronary vessels. They soften and become wide. As a result, the blood slows down its flow, the organs begin to experience discomfort, and the patient begins to feel worse.
The opposite effect is observed with an excess of potassium: the coronaries become fragile and narrow. But this also brings some troubles to the blood flow, since blood cannot enter the highways in normal quantities and be pumped to the organs. The loss of magnesium by cells, its release into the intercellular space entails the destruction of complex carbohydrates, hyperkalemia occurs.
Magnesium takes part in all metabolic processes without exception. It is a catalyst for cell division, RNA synthesis, and provides a bookmark for hereditary information. But if its concentration decreases, the cell membrane becomes an insurmountable obstacle for the trace element. Asparks magnesium helps to get into it with an additional amount of the element.
There are pitfalls here. An overdose of the drug is fraught with hypermagnesemia, and this is the cause of cardiac arrest. Therefore, self-prescription of a "harmless" drug is unacceptable.
The concentration of potassium and magnesium in the cell is especially important during pregnancy. They ensure stable development and growth of the fetus. But Asparkam is prescribed to pregnant women with great care, preferring German Panangin - a vitamin for the heart. Overdose symptoms include fatigue and dysuria.
Another nuance: a lack of potassium changes nervous excitability, and a deficiency of intracellular magnesium causes an imbalance in the generation and consumption of energy, which stimulates convulsions, numbness of the limbs, and lethargy.
Indications for taking Asparkam
The main function of Asparkam is the transport of trace elements into the cell. The drug is prescribed in the following cases:
- Deficiency of K + and Mg + in the body.
- Heart rhythm disorder.
- Ischemic heart disease, postinfarction condition.
- Extrasystole of the ventricles.
- Foxglove intolerance.
- Shock state.
- Chronic circulatory disorders.
- Atrial fibrillation.
- Heart failure.
- From 4 months it is recommended in combination with Diacarb to correct intracranial pressure. This combination is used to treat glaucoma, epilepsy, edema, gout.
Sport
This is not to say that Asparkam has a significant effect on muscle gain. Therefore, in theory, for sports it is not a drug of choice. But, nevertheless, its popularity among athletes is great. The explanation is simple: when gaining extra pounds, athletes eat a large amount of calories in the form of proteins, carbohydrates, and fats. At the same time, trace elements account for a very small part of the diet. It is clearly not enough for normal cardiac activity. Moreover, a lack of potassium and magnesium leads to high fatigue due to metabolic imbalances. Asparks in this case are irreplaceable.
Compact, easy-to-use and saturated with the necessary K + and Mg + preparation:
- Relieves fatigue.
- Compensates for micronutrient deficiencies.
- Relieves muscle weakness.
- Makes the myocardium work stable.
- Stimulates endurance.
- Prevents AMI and ONMK.
Body-building
When it comes to bodybuilding, here Asparkam acts as an excellent metabolite. It is in strength training that its side effect of muscle building is in demand. Potassium has a positive effect on the speed of metabolic reactions, magnesium is involved in protein metabolism. In this case, cell growth occurs without fat accumulation and fluid retention in the body. This is a very important point, because during training, athletes consume a large amount of water, which washes out trace elements. This means that their replenishment becomes an urgent need.
Weight loss
The rationality of taking the drug is based on the same already familiar properties of magnesium and potassium. Mg + is needed by the central nervous system, and K + helps all muscles in the body. Together they correct the water-salt balance, remove swelling. Because of this feature, Asparkam is used for weight loss: the withdrawal of fluid from the body allows you to lose weight. At the same time, the amount of body fat remains unchanged, so the drug has never been classified as a means of helping to lose weight. Taking it thoughtlessly is dangerous, because it is a metabolite, and metabolism is a very subtle substance. An excess of trace elements entails undesirable consequences, but in no way accelerates metabolic processes.
Contraindications and method of administration
There are few contraindications, but they are important:
- Individual intolerance or sensitization of the body.
- Dysfunction of the adrenal glands and kidneys.
- Myosthenia.
- Cardiogenic shock.
- Blockade 2-3 degrees.
- Metabolic acidosis.
- ARF and chronic renal failure, anuria.
- Hemolysis.
- Dehydration.
- Age under 18.
The influence of Asparkam on the body has not been studied in detail. For this reason, it is used with caution during pregnancy and is not prescribed for children. Elderly patients are also at risk, since their metabolism is slowed down a priori due to age-related changes. However, in diseases of the cardiovascular system, the agent is accepted for admission without restrictions. The usual way is to take a couple of tablets three times a day after meals.
Side effects
Asparkam has not only positive side effects, but also negative ones. They are visualized by the following symptoms:
Feeling of weakness, weakness, dizziness.
- Muscle weakness.
- Skin rashes.
- Nausea.
- Dyspepsia.
- Dry mouth.
- Bloating.
- Hypotension.
- Hyperhidrosis.
- Dyspnea.
- Vein thrombosis.
In addition, an overdose is possible, which manifests itself:
- hyperkalemia;
- hypermagnesemia;
- crimson cheeks;
- thirst;
- arrhythmia;
- convulsions;
- hypotension of the arteries;
- heart block;
- depression of the center of respiration in the brain.
These symptoms require medical advice. In general, long-term use of Asparkam requires monitoring electrolyte levels, since:
- the absolute safety of the drug has not been proven;
- when combined with tetracyclines, iron and fluorine, the drug inhibits their absorption (the interval between medications must be at least three hours);
- there is a risk of developing hyperkalemia.
Compatibility
It has a different focus. From the point of view of pharmacodynamics, the combination with diuretics, beta-blockers, cyclosporins, NSAIDs, heparin stimulates the development of asystole and arrhythmia. The combination with hormones stops this situation. Potassium ions reduce the negative effect of cardiac glycosides. Magnesium ions - neomycin, streptomycin, polymyxin. Calcium reduces the activity of magnesium, so you need to combine such funds with great care, for health reasons.
Pharmacokinetics warns of the incompatibility of Asparkam with astringent and enveloping drugs, since they reduce the absorption of the drug in the digestive tube and recommends, if necessary, observe a three-hour interval between doses.
Comparison with Panangin
Potassium and magnesium are also found in another popular drug. We are talking about Panangin. Comparative characteristics of drugs are presented in the table.
Component | Tablets | Solution | ||
Panangin | Asparkam | Panangin | Asparkam | |
Potassium aspartate | 160 mg | 180 mg | 45 mg / ml | |
Magnesium aspartate | 140 mg | 10 mg / ml | ||
Conversion to K + ions | 36 mg | |||
Conversion to Mg + ions | 12 mg | 3.5 mg / ml | ||
Aids | Silica, povidone, talc, magnesium stearate, starch, macrogol, titanium salts, metcric acid copolymers. | Starch, talc, calcium stearate, tween-80. | Injection water. | Water for injection, sorbitol. |
It is obvious that the active substances in both drugs are identical, the difference is in the cachet, which does not affect the medicinal properties of the drugs. However, Panangin has a film membrane that protects the gastric mucosa and teeth from the chemical toxicity of the agent. Therefore, everyone who has problems with the digestive system is recommended Panangin, the price of which is several times higher than the cost of Asparkam.