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Orotic acid (vitamin B13): description, properties, sources, norm

Vitamins

1K 0 02.05.2019 (last revised: 03.07.2019)

We all know about the existence of vitamin B12, but few are aware that the line of vitamins in this group has continued, and there is an element called B13. It cannot be unequivocally attributed to a full-fledged vitamin, but, nevertheless, it has properties important for the body.

Opening

In 1904, in the process of synthesizing substances contained in fresh cow's milk, two scientists discovered the presence of a previously unknown element with anabolic properties. Subsequent studies of this substance showed its presence in the milk of all mammals, including humans. The discovered substance was named "orotic acid".

And only almost 50 years after its description, scientists established a connection between orotic acid and group vitamins, recognizing their unity in molecular structure and principles of action, by that time 12 vitamins of this group had already been discovered, so the newly discovered element received serial number 13.

Characteristics

Orotic acid does not belong to the group of vitamins, it is a vitamin-like substance, since it is independently synthesized in the intestine from potassium, magnesium, and calcium supplied with food. In its pure form, orotic acid is a white crystalline powder, which is practically insoluble in water and other types of liquid, and is also destroyed under the influence of light rays.

Vitamin B13 acts as an intermediate product of the biological synthesis of nucleotides, which is characteristic of all living organisms.

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Benefits for the body

Orotic acid is required for many vital processes:

  1. Takes part in the synthesis of photolipids, which leads to the strengthening of the cell membrane.
  2. It activates the synthesis of nucleic acids, which play an important role in the growth process of the body.
  3. Increases the production of erythrocytes and leukocytes, improving their quality.
  4. It has an anabolic effect, which consists in a gradual increase in muscle mass by activating protein synthesis.
  5. Improves the quality of reproductive function.
  6. Reduces cholesterol levels, preventing its deposition on the walls of blood vessels.
  7. Promotes the production of hemoglobin, bilirubin.
  8. Reduces the amount of uric acid produced.
  9. Protects the liver from obesity.
  10. Promotes the breakdown and elimination of glucose.
  11. Reduces the risk of premature aging.

Indications for use

Vitamin B13 is used as an auxiliary source in the complex therapy of various diseases:

  • Heart attack, angina pectoris and other diseases of the cardiovascular system.
  • Dermatitis, dermatoses, skin rashes.
  • Liver disease.
  • Atherosclerosis.
  • Muscle dystrophy.
  • Motor function disorders.
  • Anemia.
  • Gout.

Orotic acid is taken during the recovery period after prolonged illness, as well as with regular sports training. It increases appetite, preserves the health of the fetus during pregnancy, if indicated by a doctor.

The body's need (instructions for use)

Determination of the deficiency of vitamin B13 in the body can be done using a vitamin analysis. As a rule, if everything is in order, it is synthesized in sufficient quantity. But under intense loads it is consumed much faster and often requires additional intake.

The daily requirement for orotic acid depends on various factors: a person's condition, age, level of physical activity. Scientists have derived an average that determines the amount of daily acid intake.

CategoryDaily requirement, (g)
Children over a year old0,5 – 1,5
Children under one year old0,25 – 0,5
Adults (over 21)0,5 – 2
Pregnant and lactating women3

Contraindications

The supplement should not be taken if:

  • Ascites caused by liver cirrhosis.
  • Renal failure.

Content in food

Vitamin B13 is able to be synthesized in the intestines, supplemented by the amount that comes from food.

© alfaolga - stock.adobe.com

Products *Vitamin B13 content (g)
Brewer's yeast1,1 – 1,6
Animal liver1,6 – 2,1
Sheep milk0,3
Cow's milk0,1
Natural fermented milk products;Less than 0.08 g
Beets and carrotsLess than 0.8

* Source - wikipedia

Interaction with other trace elements

Taking vitamin B13 accelerates the absorption of folic acid. He is able to replace vitamin B12 for a short time in case of an emergency deficiency. Helps neutralize the side effects of many antibiotics.

Vitamin B13 Supplements

NameManufacturerRelease formDosage (gr.)Method of receptionprice, rub.
Potassium orotate

AVVA RUSTablets

Granules (for children)

0,5

0,1

Athletes take 3-4 tablets a day. The duration of the course is 20-40 days. Recommended to be combined with Riboxin.180
Magnesium orotate

WOERWAG PHARMATablets0,52-3 tablets a day for a week, the remaining three weeks - 1 tablet 2-3 times a day.280

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Watch the video: 12 Signs of Vitamin B12 and Folate Deficiency (June 2025).

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